Of DermaPure's ten ingredients, this is the one that needs a genuine safety conversation rather than a marketing paragraph. It isn't a reason not to buy — it's a reason to do two specific things if you do.
Babchi is the seed and powder of Psoralea corylifolia, a plant with long documented use in Ayurvedic and traditional Chinese medicine, historically for skin conditions including vitiligo and psoriasis.
The plant contains psoralens — compounds that increase the skin's sensitivity to ultraviolet light.
This is not a fringe concern or a precautionary guess. Psoralens are used medically for exactly this property: PUVA therapy combines psoralen with controlled UVA exposure under medical supervision to treat psoriasis and vitiligo. The historical use of babchi for vitiligo works through the same mechanism.
Case reports of liver injury associated with oral Psoralea corylifolia preparations exist in the published literature. These are individual reports rather than trial findings, and typically involve concentrated preparations rather than a small share of a 430 mg blend — but they're real, and they're a reason for anyone with an existing liver condition to speak to a doctor before starting.
You've likely seen bakuchiol marketed as "nature's retinol," with some encouraging trial data for skin texture and fine lines. Bakuchiol is a single compound isolated from this same plant.
But that research concerns bakuchiol applied topically at a controlled concentration. DermaPure contains babchi powder taken orally, at an undisclosed amount inside a blend. Different compound preparation, different route, different dose — and therefore a different evidence base.
Any page citing bakuchiol trials to support an oral babchi supplement is making a leap it hasn't earned.
Not automatically, and framing it that way would be dishonest. The amount in a shared 430 mg blend is likely small, the traditional use is genuine, and millions of people wear daily sunscreen without thinking about it.
It is a reason to do three things: wear sun protection consistently, clear it with a doctor if you have a liver condition or take photosensitising medication, and treat "natural retinol" marketing with appropriate scepticism. See the full safety section.
Read next: the full graded label, or the skin timeline.